Cryptic crossword clue
Groups of notes hard to get in strings 6

The most common and most likely answer to this crossword clue is the 6 letter word CHORDS

C
H
O
R
D
S

Buddy explains!

The straight part
We know that "Groups of notes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case groups of notes = chords.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CHORDS mean?

CHORDS noun
  1. A harmonic set of three or more notes that is heard as if sounding simultaneously.
  2. A straight line between two points of a curve.
  3. A horizontal member of a truss.
  4. The distance between the leading and trailing edge of a wing, measured in the direction of the normal airflow.
  5. An imaginary line from the luff of a sail to its leech.
  6. A keyboard shortcut that involves two or more distinct keypresses, such as Ctrl+M followed by P.
  7. The string of a musical instrument.
  8. A cord.
  9. An edge that is not part of a cycle but connects two vertices of the cycle.

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