Cryptic crossword clue
Groups run away from poor stone cutter 8

The most common and most likely answer to this crossword clue is the 8 letter word OCTETTES

I've seen this crossword clue in Financial Times
O
C
T
E
T
T
E
S

Buddy explains!

The straight part
We know that "Groups" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case groups = octettes.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OCTETTES mean?

OCTETTES noun
  1. A group or set of eight of something.
  2. A group of eight musicians performing together.
  3. A composition for such a group of musicians.
  4. A byte of eight bits. Abbreviation: o
  5. A group of three bits, representing any of eight possible values.

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