Cryptic crossword clue
Gruesomely large openings on total wreck of part of larynx 7

The most common and most likely answer to this crossword clue is the 7 letter word GLOTTAL

I've seen this crossword clue in The Guardian
G
L
O
T
T
A
L

Buddy explains!

The straight part
We know that "of part of larynx" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case of part of larynx = glottal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GLOTTAL mean?

GLOTTAL noun
  1. A sound made with the glottis
GLOTTAL adjective
  1. Of or relating to the glottis.
  2. Articulated with the glottis.

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