Cryptic crossword clue
Guard for stripper’s lead appearance 6

The most common and most likely answer to this crossword clue is the 6 letter word SENTRY

I've seen this crossword clue in Financial Times
S
E
N
T
R
Y

Buddy explains!

The straight part
We know that "Guard" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case guard = sentry.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SENTRY mean?

SENTRY noun
  1. A guard, particularly on duty at the entrance to a military base.
  2. Sentry duty; time spent being a sentry.
  3. A form of drag to be towed underwater, which on striking bottom is upset and rises to the surface.
  4. A watchtower.

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