The most common and most likely answer to this crossword clue is the 9 letter word SENTINELS
I've seen this crossword clue in The Guardian
S
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More clues leading to the result SENTINELS
Buddy explains!
The straight part
We know that "Guards" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case guards = sentinels.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SENTINELS mean?
SENTINELS noun- A sentry, watch, or guard.
- A private soldier.
- A unique string of characters recognised by a computer program for processing in a special way; a keyword.
- A sentinel crab.
- A sign of a health risk (e.g. a disease, an adverse effect).