Cryptic crossword clue
  Hancock said his bloody pint was almost this toxic? Not initially 6

The most common and most likely answer to this crossword clue is the 6 letter word ARMFUL

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Hancock said his bloody pint was almost this" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hancock said his bloody pint was almost this = armful.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ARMFUL mean?

ARMFUL noun
  1. The amount an arm or arms can hold.

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