The most common and most likely answer to this crossword clue is the 5 letter word HORAL
H
O
R
A
L
Buddy explains!
The straight part
We know that "every sixty minutes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case every sixty minutes = horal.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HORAL mean?
HORAL adjective- Of or relating to an hour, or to hours.