The most common and most likely answer to this crossword clue is the 5 letter word HANDY
I've seen this crossword clue in The Times
H
A
N
D
Y
More clues leading to the result HANDY
- Hard man with practical skills
- Hospital with pharmacy ultimately within easy reach
- Practical characters at borders of Hungary?
- Practical arrangement of Haydn
- Near neighbours buried in churchyard
- Hungary’s borders accessible
- Useful hockey sides
- Convenient Haydn composition
- Useful imperative when starting to write hymn
- 20 Helpful, splendid husband for first daughter
Buddy explains!

The straight part
We know that "with practical skills" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with practical skills = handy.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HANDY mean?
HANDY adjective- Easy to use, useful.
- Nearby, within reach.
- Of a person: dexterous, skilful.
- Physically violent; tending to use one's fists.
- Of a freight ship: having a small cargo capacity (less than 40,000 DWT); belonging to the handysize class.
- A hand job.
- A handgun.