Cryptic crossword clue
Harmful liquid from Roman well sort of Buddhist swallowed 7

The most common and most likely answer to this crossword clue is the 7 letter word BENZENE

I've seen this crossword clue in The Times
B
E
N
Z
E
N
E

Buddy explains!

The straight part
We know that "Harmful liquid" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case harmful liquid = benzene.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BENZENE mean?

BENZENE noun
  1. An aromatic hydrocarbon of formula C6H6 whose structure consists of a ring of alternate single and double bonds.
  2. (in combination) Sometimes used in place of the phenyl group.

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