Cryptic crossword clue
Harmful worms almost cram a valley 7

The most common and most likely answer to this crossword clue is the 7 letter word FILARIA

F
I
L
A
R
I
A

Buddy explains!

The straight part
We know that "Harmful worms" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case harmful worms = filaria.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FILARIA mean?

FILARIA noun
  1. Any of the parasitic nematode worms of superfamily Filarioidea that live in the blood of vertebrates and is transmitted by insects: the cause of filariasis.

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