Cryptic crossword clue
Harry and Mary — one of them works on the railway 7

The most common and most likely answer to this crossword clue is the 7 letter word YARDMAN

I've seen this crossword clue in The Guardian
Y
A
R
D
M
A
N


Buddy explains!

The straight part
We know that "one of them works on the railway" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one of them works on the railway = yardman.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does YARDMAN mean?

YARDMAN noun
  1. A worker in a railway yard.
  2. A laborer hired to do outdoor work.

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