The most common and most likely answer to this crossword clue is the 6 letter word UPSHOT
I've seen this crossword clue in The Guardian
U
P
S
H
O
T
More clues leading to the result UPSHOT
- Result of photo of the sky?
- Result of winning stroke
- Conclusion done, go
- Consequence of having risen dramatically following exchange
- Result involved in hitting a six?
- Outcome of lob?
- Result of competitions having missed lead piping
- Final issue finished, executed
- Harry Hotspur runs away in sequel
- Raises spicy product
Buddy explains!

The straight part
We know that "sequel" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sequel = upshot.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does UPSHOT mean?
UPSHOT noun- A concise summary.
- The final result, or outcome of something.