The most common and most likely answer to this crossword clue is the 3 plus 4 plus 10 plus 2 plus 6 letter word THE LAST TEMPTATION OF CHRIST
I've seen this crossword clue in The Guardian
T
H
E
L
A
S
T
T
E
M
P
T
A
T
I
O
N
O
F
C
H
R
I
S
T
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.