Cryptic crossword clue
Harsh and bitter bishop in command, pursuing one regime at first 7

The most common and most likely answer to this crossword clue is the 7 letter word ACERBIC

A
C
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B
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C


Buddy explains!

The straight part
We know that "Harsh and bitter" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case harsh and bitter = acerbic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACERBIC mean?

ACERBIC adjective
  1. Tasting sour or bitter.
  2. Sharp, harsh, biting.

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