The most common and most likely answer to this crossword clue is the 8 letter word FREEBASE
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does FREEBASE mean?
FREEBASE noun- The purified, dry form of an amine, especially an alkaloid natural product, that is normally used in solution.
- (specifically) The purified, dry form of certain illegal drugs, especially cocaine.
- To purify a drug by crystallization.
- To use a purified drug, especially cocaine, by heating it and inhaling the fumes produced.