The most common and most likely answer to this crossword clue is the 3 plus 6 plus 3 plus 3 letter word SEE NAPLES AND DIE
I've seen this crossword clue in The Daily Telegraph
S
E
E
N
A
P
L
E
S
A
N
D
D
I
E
More clues leading to the result SEE NAPLES AND DIE
- Lethal advice to tourists in Italy?
- Advice to tourists on the west coast of Italy that may be misconstrued?
- Statement, perhaps made to tourists in Campania, denies esplanade needs rebuilding
- Have one last exotic trip, using various seaplanes indeed
- How to spend holiday in Italy that could be murder
- . Place primarily to be covered, sense a deadline's involved going by this travel advice
- Film shown as Nepalese dined out?
Buddy explains!
The straight part
We know that "Have one last exotic trip" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case have one last exotic trip = see naples and die.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.