Cryptic crossword clue
Having no hope of fixing 24 7

The most common and most likely answer to this crossword clue is the 7 letter word DESPAIR

I've seen this crossword clue in The Guardian
D
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Buddy explains!

The straight part
We know that "Having no hope" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case having no hope = despair.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DESPAIR mean?

DESPAIR noun
  1. Loss of hope; utter hopelessness; complete despondency.
  2. That which causes despair.
  3. That which is despaired of.
DESPAIR verb
  1. To give up as beyond hope or expectation; to despair of.
  2. To cause to despair.
  3. (often with “of”) To be hopeless; to have no hope; to give up all hope or expectation.

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