The most common and most likely answer to this crossword clue is the 14 letter word NANOTECHNOLOGY
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More clues leading to the result NANOTECHNOLOGY
Buddy explains!
The straight part
We know that "creation of tiny things" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case creation of tiny things = nanotechnology.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NANOTECHNOLOGY mean?
NANOTECHNOLOGY noun- The science and technology of creating nanoparticles and of manufacturing machines which have sizes within the range of nanometres.