Cryptic crossword clue
He chooses reader following directions

The most common and most likely answer to this crossword clue is the 8 letter word SELECTOR

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "He chooses" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case he chooses = selector.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SELECTOR mean?

SELECTOR noun
  1. Someone or something which selects or chooses.
  2. An administrator responsible for selecting which players will play for a side.
  3. A matching expression in a stylesheet determining which elements in the markup are affected by a style.
  4. A pointer to a structure describing a segment of memory.
  5. A text string transmitted to a Gopher server, identifying the resource to be retrieved.
  6. A disc jockey.

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