The most common and most likely answer to this crossword clue is the 6 letter word ERNEST
I've seen this crossword clue in The Guardian
E
R
N
E
S
T
More clues leading to the result ERNEST
Buddy explains!

The straight part
We know that "He/He" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case he/he = ernest.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.