Cryptic crossword clue
Heads of local office to set up and initiate office at station? 4,3,5

The most common and most likely answer to this crossword clue is the 4 plus 3 plus 5 letter word LOST AND FOUND

I've seen this crossword clue in The Times
L
O
S
T
A
N
D
F
O
U
N
D

Buddy explains!

The straight part
We know that "office at station?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case office at station? = lost and found.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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