Cryptic crossword clue
Heart-throb may be strangely isolated 8

The most common and most likely answer to this crossword clue is the 8 letter word DIASTOLE

I've seen this crossword clue in The Daily Telegraph
D
I
A
S
T
O
L
E


Buddy explains!

The straight part
We know that "Heart-throb" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case heart-throb = diastole.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DIASTOLE mean?

DIASTOLE noun
  1. The phase or process of relaxation and dilation of the heart chambers, between contractions, during which they fill with blood; an instance of the process.
  2. The lengthening of a vowel or syllable beyond its typical length.
  3. (Greek grammar) The hypodiastole, a textual or punctuation mark formerly used to disambiguate homonyms in Greek.

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