Cryptic crossword clue
Heartlessly trick old Venetian 4

The most common and most likely answer to this crossword clue is the 4 letter word DOGE

I've seen this crossword clue in The Times
D
O
G
E


Buddy explains!

The straight part
We know that "old Venetian" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case old venetian = doge.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DOGE mean?

DOGE noun
  1. The chief magistrate in the republics of Venice and Genoa.
DOGE noun
  1. A dog.
  2. Specifically, a Shiba Inu, as in the doge meme.

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