The most common and most likely answer to this crossword clue is the 6 letter word BUSTER
I've seen this crossword clue in Financial Times
B
U
S
T
E
R
More clues leading to the result BUSTER
Buddy explains!
The straight part
We know that "address for American guy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case address for american guy = buster.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BUSTER mean?
BUSTER noun- (with 'of') Someone who or something that bursts, breaks, or destroys a specified thing.
- Forming compounds denoting a team, weapon, or device specialized in the destruction of the first element.
- (with 'of') Someone who or something that 'breaks', tames, or overpowers a specified person or thing.
- Someone or something remarkable, especially for being loud, large, etc..
- A loaf of bread.
- A drinking spree, a binge.
- A gale, a strong wind; a southerly buster.
- A heavy fall; a staged fall, a pratfall.
- A molting crab.