The most common and most likely answer to this crossword clue is the 5 plus 4 letter word RAISE CAIN
I've seen this crossword clue in The Guardian
R
A
I
S
E
C
A
I
N
More clues leading to the result RAISE CAIN
- Make trouble, as Adam and Eve were destined to do
- Hit the roof, as Adam did
- Being fine and dry inside, showers hit the roof
- Kick up a fuss, as Adam and Eve did
- Protest heatedly when canaries are mistreated? I’ll participate
- Reportedly, skates stick and cause trouble
- Heatedly protest Spooner’s shortened king’s time in power
- Step up — one entering may become very angry
- Make a fuss about pub shortly after increase
- Cause a fuss like the First Lady did?
Buddy explains!

The straight part
We know that "Hit the roof" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hit the roof = raise cain.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.