The most common and most likely answer to this crossword clue is the 5 letter word GRASP
I've seen this crossword clue in The Times
G
R
A
S
P
More clues leading to the result GRASP
Buddy explains!

The straight part
We know that "Hold" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hold = grasp.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GRASP mean?
GRASP noun- (sometimes figurative) Grip.
- Understanding.
- That which is accessible; that which is within one's reach or ability.
- To grip; to take hold, particularly with the hand.
- To understand.
- To take advantage of something, to seize, to jump at a chance.