Cryptic crossword clue
Hold over nerd peculiarly having outgrowth on head 6

The most common and most likely answer to this crossword clue is the 6 letter word HORNED

H
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Buddy explains!

The straight part
We know that "having outgrowth on head" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case having outgrowth on head = horned.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HORNED mean?

HORNED adjective
  1. Having horns.
  2. Cuckolded
HORNED verb
  1. (of an animal) To assault with the horns.
  2. To furnish with horns.
  3. To cuckold.

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