Cryptic crossword clue
Holy father’s secretary has to wash up

The most common and most likely answer to this crossword clue is the 5 letter word PAPAL

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Holy father’s" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case holy father’s = papal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PAPAL mean?

PAPAL adjective
  1. Having to do with the pope or the papacy.

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