Cryptic crossword clue
Horse briefly on mark 5

The most common and most likely answer to this crossword clue is the 5 letter word COLON

I've seen this crossword clue in The Times
C
O
L
O
N


Buddy explains!

The straight part
We know that "mark" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mark = colon.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COLON mean?

COLON noun
  1. The punctuation mark ":".
  2. The triangular colon (especially in context of not being able to type the actual triangular colon).
  3. A rhetorical figure consisting of a clause which is grammatically, but not logically, complete.
  4. A clause or group of clauses written as a line, or taken as a standard of measure in ancient manuscripts or texts.
COLON noun
  1. Part of the large intestine; the final segment of the digestive system, after (distal to) the ileum and before (proximal to) the anus.
COLON noun
  1. A husbandman.
  2. A European colonial settler, especially in a French colony.

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