Cryptic crossword clue
Hotel niff picked up on odd occasions, result of lack of cleaning? 5

The most common and most likely answer to this crossword clue is the 5 letter word FILTH

I've seen this crossword clue in The Times
F
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H

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The straight part
We know that "result of lack of cleaning" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case result of lack of cleaning = filth.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FILTH mean?

FILTH noun
  1. Dirt; foul matter; that which soils or defiles.
  2. Smut; that which sullies or defiles the moral character; corruption; pollution.
  3. (with definite article) The police.
  4. A vile or disgusting person.
  5. Weeds growing on pasture land.

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