The most common and most likely answer to this crossword clue is the 12 letter word RECEPTIONIST
I've seen this crossword clue in The Guardian
R
E
C
E
P
T
I
O
N
I
S
T
Buddy explains!

The straight part
We know that "Hotel worker" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hotel worker = receptionist.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RECEPTIONIST mean?
RECEPTIONIST noun- An employee (such as a secretary) who works in reception (receiving visitors and/or calls) for a person or business, especially an office.
- A proponent of receptionism.