Cryptic crossword clue
House accommodating a domineering woman 6

The most common and most likely answer to this crossword clue is the 6 letter word VIRAGO

V
I
R
A
G
O


Buddy explains!

The straight part
We know that "domineering woman" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case domineering woman = virago.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VIRAGO mean?

VIRAGO noun
  1. A woman given to undue belligerence or ill manner at the slightest provocation.
  2. A woman who is scolding, domineering, or highly opinionated.
  3. A woman who is rough, loud, and aggressive.

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