The most common and most likely answer to this crossword clue is the 6 letter word FUDDLE
F
U
D
D
L
E
Buddy explains!

The straight part
We know that "state of confusion" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case state of confusion = fuddle.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does FUDDLE mean?
FUDDLE noun- Intoxication.
- Intoxicating drink; liquor.
- Muddle, confusion.
- A party or picnic where attendees bring food and wine; a kind of potluck.
- To confuse or befuddle.
- To intoxicate.
- To become intoxicated; to get drunk.