Cryptic crossword clue
Huge number, male or female, given work at home, love to get stuck in 10

The most common and most likely answer to this crossword clue is the 10 letter word SEXTILLION

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Buddy explains!

The straight part
We know that "Huge number" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case huge number = sextillion.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SEXTILLION mean?

SEXTILLION numeral
  1. (US; modern British & Australian, short scale) A trillion billion: 1 followed by 21 zeros, 1021.
  2. (dated British & Australian, long scale) A million quintillion: 1 followed by 36 zeros, 1036.

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