Cryptic crossword clue
Hum very loudly after turning in 4

The most common and most likely answer to this crossword clue is the 4 letter word NIFF

N
I
F
F

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The straight part
We know that "Hum" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hum = niff.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NIFF mean?

NIFF noun
  1. A bad smell.
NIFF verb
  1. To smell bad; to stink.

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