Cryptic crossword clue
Hundred and one leaving concern in loneliness  8

The most common and most likely answer to this crossword clue is the 8 letter word SOLITUDE

S
O
L
I
T
U
D
E


Buddy explains!

The straight part
We know that "loneliness" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case loneliness = solitude.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SOLITUDE mean?

SOLITUDE noun
  1. Aloneness; state of being alone or solitary, by oneself.
  2. A lonely or deserted place.

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