The most common and most likely answer to this crossword clue is the 8 plus 2 plus 4 letter word RHAPSODY IN BLUE
R
H
A
P
S
O
D
Y
I
N
B
L
U
E
More clues leading to the result RHAPSODY IN BLUE
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.