Cryptic crossword clue
I break in to lodge by river and hold Bill up 10

The most common and most likely answer to this crossword clue is the 10 letter word FILIBUSTER

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "hold Bill up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hold bill up = filibuster.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FILIBUSTER mean?

FILIBUSTER noun
  1. A mercenary soldier; a freebooter; specifically, a mercenary who travelled illegally in an organized group from the United States to a country in Central America or the Spanish West Indies in the mid-19th century seeking economic and political benefits through armed force.
  2. (US politics) A tactic (such as giving long, often irrelevant speeches) employed to delay the proceedings of, or the making of a decision by, a legislative body, particularly the United States Senate.
  3. (US politics) A member of a legislative body causing such an obstruction; a filibusterer.
FILIBUSTER verb
  1. To take part in a private military action in a foreign country.
  2. To use obstructionist tactics in a legislative body.

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