The most common and most likely answer to this crossword clue is the 10 letter word INDIGENOUS
I
N
D
I
G
E
N
O
U
S
Buddy explains!
The straight part
We know that "home-grown" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case home-grown = indigenous.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
Crossword Answer definitions
INDIGENOUS adjective- Born or originating in, native to a land or region, especially before an intrusion.
- Innate, inborn.