The most common and most likely answer to this crossword clue is the 2 letter word IT
I
T
More clues leading to the result IT
- What a coincidence Pluto could be described thus
- Show insight, adamant at changes after head of department is sacked
- Newly detained suspect might utter this terribly grave prognosis for tough guy: “A ‘Titanic’ tomb!”
- Curry in 1990, dredged from sewer and refried in 2017
- 25d, 13a & 22a Very ill, one last breath left, artiste finally composed his last words
- I didn’t expect to see you as old — still warm. Let it all go …
- 8d’s objective. What is it?
- Description of diamond essentially fits London building
- Satellite? Moon? Somehow I’m not bothered
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does IT mean?
IT noun- One who is neither a he nor a she; a creature; a dehumanized being.
- The person who chases and tries to catch the other players in the playground game of tag.
- The game of tag.
- Sex appeal, especially that which goes beyond beauty.
- Sexual activity.
- A biological force that inhabits living beings, according to the vitalist approach of Georg Groddeck.
- Most fashionable.
- The third-person singular personal pronoun that is normally used to refer to an inanimate object or abstract entity, also often used to refer to animals.
- A third-person singular personal pronoun used to refer to a child, especially of unknown gender.
- Used to refer to someone being identified, often on the phone, but not limited to this situation.
- The impersonal pronoun, used without referent as the subject of an impersonal verb or statement. (known as the dummy pronoun or weather it)
- The impersonal pronoun, used without referent in various short idioms.
- The impersonal pronoun, used as a placeholder for a delayed subject, or less commonly, object; known as the dummy pronoun or, more formally in linguistics, a syntactic expletive. The delayed subject is commonly a to-infinitive, a gerund, or a noun clause introduced by a .
- All or the end; something after which there is no more.
- A third-person singular personal pronoun used to refer to an animate referent who is transgender or is neither female nor male.
- Followed by an omitted and understood relative pronoun: That which; what.
- A large peninsula in Southern Europe protruding into the Mediterranean Sea and shaped like a boot. The mountain range of Apennines runs across it from north to south. Occupied almost entirely by Italy.
- A country in southern Europe. Official name: Italian Republic.
- Abbreviation of Italian. (language)