Cryptic crossword clue
I don’t believe host is at party 2,4,2

The most common and most likely answer to this crossword clue is the 2 plus 4 plus 2 letter word IS THAT SO

I've seen this crossword clue in The Guardian
I
S
T
H
A
T
S
O

Buddy explains!

The straight part
We know that "I don’t believe" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case i don’t believe = is that so.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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