Cryptic crossword clue
I go my way, being of a different persuasion 5

The most common and most likely answer to this crossword clue is the 5 letter word GOYIM

I've seen this crossword clue in The Guardian
G
O
Y
I
M

Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GOYIM mean?

GOYIM noun
  1. A non-Jew, a gentile. (See usage notes)

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