Cryptic crossword clue
I, grandmother in Delhi, not one to buckle in lassitude 9

The most common and most likely answer to this crossword clue is the 9 letter word INANITION

I
N
A
N
I
T
I
O
N

Buddy explains!

The straight part
We know that "lassitude" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lassitude = inanition.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INANITION mean?

INANITION noun
  1. The act of removing the contents of something; the state of being empty.
  2. A state of advanced lack of adequate nutrition, food, or water or a physiological inability to utilize them, with resulting weakness; starvation or cachexia.
  3. A spiritual emptiness or lack of purpose or will to live, akin to the Existentialist Philosophy state of "nausea".

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