Cryptic crossword clue
I run away from criminal suspect with hostile attitude 8

The most common and most likely answer to this crossword clue is the 8 letter word INIMICAL

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Buddy explains!

The straight part
We know that "with hostile attitude" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with hostile attitude = inimical.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INIMICAL mean?

INIMICAL adjective
  1. Harmful in effect.
  2. Unfriendly, hostile.

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