Cryptic crossword clue
I sensed vices destroyed ability to resolve issues 12

The most common and most likely answer to this crossword clue is the 12 letter word DECISIVENESS

I've seen this crossword clue in The Times
D
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Buddy explains!

The straight part
We know that "ability to resolve issues" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ability to resolve issues = decisiveness.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

DECISIVENESS noun
  1. The state or quality of being decisive.

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