Cryptic crossword clue
I take off from island with German ace, going over to Rome initially 8

The most common and most likely answer to this crossword clue is the 8 letter word IMITATOR

I've seen this crossword clue in The Daily Telegraph
I
M
I
T
A
T
O
R


Buddy explains!

The straight part
We know that "I take off" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case i take off = imitator.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IMITATOR mean?

IMITATOR noun
  1. One who imitates or apes another.

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