Cryptic crossword clue
I’d hip and heart replaced in serious illness 10

The most common and most likely answer to this crossword clue is the 10 letter word DIPHTHERIA

I've seen this crossword clue in The Daily Telegraph
D
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Crossword Answer definitions

DIPHTHERIA noun
  1. A serious infectious disease which causes inflammation of mucous membranes of the upper respiratory tract caused by Corynebacterium diphtheriae.

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