Cryptic crossword clue
If emptied sample went missing, this star would be at risk 8

The most common and most likely answer to this crossword clue is the 8 letter word ASTERISK

I've seen this crossword clue in Financial Times
A
S
T
E
R
I
S
K


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ASTERISK mean?

ASTERISK noun
  1. The symbol *.
  2. Something in the shape of or resembling the asterisk symbol.
  3. A blemish in an otherwise outstanding achievement.
ASTERISK verb
  1. To mark or replace with an asterisk symbol (*); star.

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