Cryptic crossword clue
Ignoring regular indications in diagnosis is concerning, principally relating to part of the eye 8

The most common and most likely answer to this crossword clue is the 6 plus 3 letter word IRIDIC (-)

I've seen this crossword clue in The Guardian
I
R
I
D
I
C
(
-
)

Buddy explains!

The straight part
We know that "relating to part of the eye" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case relating to part of the eye = iridic (-).
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.


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