Cryptic crossword clue
Ill-disposed to clam up about new hospital department 10

The most common and most likely answer to this crossword clue is the 10 letter word MALCONTENT

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Buddy explains!

The straight part
We know that "Ill-disposed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ill-disposed = malcontent.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MALCONTENT mean?

MALCONTENT noun
  1. A person who is not satisfied with current conditions; a discontented person, a rebel.
  2. A state of discontentment or dissatisfaction; something that causes discontent.
MALCONTENT verb
  1. To cause discontent or dissatisfaction.
MALCONTENT adjective
  1. Dissatisfied with current conditions; disaffected, discontented, rebellious.

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